Pharmacokinetic Plasma Clearance Model
GLP-1 Elimination Half-Life & Bloodstream Clearance Calculator
Model how much Semaglutide or Tirzepatide remains in your bloodstream after injection, estimate time to complete drug washout, and anticipate appetite rebound timing.
Pharmacokinetic Parameters
Days Since Last Injection:3 Days
Day 0 (Injection)Day 7 (Next Dose)Day 35 (Washout)
Steady-State Accumulation: Because GLP-1 half-lives exceed several days, active drug compounds accumulate with each weekly injection until reaching steady state around Week 4–5.
Pharmacokinetic Output
Estimated Active Plasma ConcentrationDay 3
74% (0.74 mg)
Elimination Half-Life
7 Days
Time to reduce 50%
Total Systemic Clearance
~35 Days
5 half-life elimination
Appetite Rebound Probability:
Suppressed (Peak Satiety)
Drug concentration is elevated. Gastric emptying remains slowed. Focus on cold, gentle, highly bioavailable protein purees.
Automate your nutrition around your Cmax curve
FitFighter automatically assigns liquid protein on your peak concentration days and solid high-satiety meals on your clearance days.
Build Chrono Schedule for Your Injection Curve →